Aisha Adil
Aisha is an MSc graduate student through Institute of Medical Science at University of Toronto under the supervision of Dr. Siba Haykal and Dr. Golnaz Karoubi. Her research location is in Latner Thoracic Surgical Research Laboratories at University Health Network. Aisha previously obtained an Honours Bachelor of Science at the University of Toronto, with a specialization in Health and Disease before proceeding to graduate studies. Her research focuses on tissue engineering composite rat hindlimbs using tissue de- and recellularization for vascular composite allotransplantation (VCA). She has published her work on decellularization of the rat hindlimb and is currently assessing recellularization strategies. She is a recipient of numerous awards including the Banting and Best Canada Graduate Scholarship (CGS-M). She has presented her graduate work at various conferences locally and nationally. She aspires to continue in academia medicine by pursuing further doctorate training through a clinician-scientist pathway.
This session will highlight the most innovative studies our trainees are working on across the themes. Chelsea Lanos, representing themes 1 and 2, will present her project "Organ donation after out-of-hospital cardiac arrest in Canada: a missed opportunity for uDCD?". For theme 3, we have Shiyuan Bian presenting "Investigating the Effect of Mechanical Ventilation on Mouse Lung Scaffolds using a Negative Pressure Wet Ventilation System" and Aisha Adil presenting "Ex Vivo Perfusion De- and Recellularization of Rat Hindlimbs for Vascular Composite Allotransplantation." Javairia Rahim will cover theme 4 with her project "Novel cell surface engineering of the endothelial glycocalyx with sialic acid-containing polymers for the prevention of transplant rejection." Finally, Nicholas Bourgeois will present "Virtual pre-habilitation program in lung transplant candidates" for theme 5. Each of these students will be awarded a prize highlighting their excellent work.
Moderators: Francis Migneault & Jorge Castillo-Prado
This session is supported by the Canadian Institutes of Health Research (CIHR).
Speakers: Nicholas Bourgeois, Aisha Adil, Chelsea Lanos, Javairia Rahim, Shiyuan Bian
The future application of designer cells and bioengineered tissues in clinical settings holds immense promise for revolutionizing regenerative medicine and transplantation, yet it also confronts significant feasibility challenges. The ability to precisely tailor cells and tissues for therapeutic purposes can have significant impact in transplantation opening avenues for personalized medicine and access to ‘off-the-shelf’ tissues and organs. However, the translation of these cutting-edge technologies from the laboratory to clinical practice requires overcoming formidable hurdles, including safety concerns, ethical considerations, community acceptance and the need for robust regulatory frameworks. Technical challenges such as the scalability and cost-effectiveness of producing designer cells and tissues also present major logistical challenges. As research continues to push the boundaries of synthetic biology and tissue engineering, the ultimate success and integration of designer cells and bioengineered tissues in the medical landscape will require close collaboration from scientists, clinicians, and policymakers; and importantly communication with patient communities, some of whom, will be future recipients of these new therapeutic modalities.
This session is supported by the Canadian Institutes of Health Research (CIHR).
Session Chairs:
- Dr. Golnaz Karoubi (Senior Chair) – University Health Network, University of Toronto
- Ms. Aisha Adil (Junior Chair) – University Health Network, University of Toronto
Panelists:
- Dr. Siba Haykal - University Health Network/University of Toronto
- Dr. Ian Rogers – Sinai Health Systems/University of Toronto
- Dr. Braulio Marfil-Garza – University of Alberta
- Mr. Sean Delaney – University of Alberta
Speakers: Siba Haykal, Golnaz Karoubi, Aisha Adil, Braulio Marfil-Garza, Sean Delaney, Ian Rogers
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